| | How can a motor response be mapped onto the brain? The protocol for motor cortex mapping consists of positioning the coil at a number of different sites, single pulse TMS at the sites, and successive recording of the evoked motor potential (MEP) of a selected muscle. The position of the coil, its electrical properties, and the evoked responses are then used to calculate the cortical representation site of the selected muscle.
When the stimulation responses for stimulation at all planned sites have been recorded, the data is used to calculate the most likely statistical representation point of the muscle on the cortex. This approach is based on a calculation of a likelihood map, evaluating the correspondence between the electric field strength at points on the cortex and the motor responses using Kendalls statistics.
Matthaus L, Trillenberg P, Fadini T, Finke M, Schweikard A. Brain mapping with transcranial magnetic stimulation using a refined correlation ratio and Kendalls tau. Stat Med. 2008 Nov 10;27(25):5252-70. |  | |